The Organization of Pakistani Entrepreneurs (OPEN) is a voluntary not-for-profit association dedicated to the promotion of entrepreneurship and professional excellence within the Pakistani-American community. The organization was formed in 1998 by a group of Pakistani-American entrepreneurs and corporate executives and registered in Massachusetts in 2000. The association's charter is to provide networking opportunities and enhanced business opportunities for entrepreneurs and professionals of Pakistani heritage in North America. OPEN meetings and events are open to the public. OPEN has chapters in Boston, Silicon Valley, Washington DC, Houston, Chicago and New York.

OPEN Chapters have Charter Memberships comprising the most successful Pakistanis in various fields such as: finance, technology, telecommunications, biotech and consulting.  OPEN regularly organizes events pertaining to current issues in business and entrepreneurship, including OPEN Speaker Series, featuring prominent industry leaders’ views on current trends; OPEN Forum, all day conference covering relevant business issues; OPEN Mentorship Dinner Series, one-on-one dinners with OPEN Charter Members; OPEN Career Day; OPEN Business Plan Competition; etc.